The Acuity Platform identifies potential targets based on assembled biological evidence and scores them with a proprietary ranking system to suggest which targets warrant experimental investment
Acuity Technologies Ltd has made a step change in target discovery and selection strategies.
Multiple independent evidence streams sit behind the Acuity Platform. Scores are tested for robustness and for reproducibility.
Ferroptosis is an iron-dependent form of cell death driven by lipid peroxidation, implicated in cancer, neurodegeneration, cardiovascular disease and inflammation.
Because those diseases affect very large patient populations, it was chosen as Acuity's first application.
The same methods apply to other biological systems and data sets.
Acuity's platform was built on groundwork laid by domain experts in cell-death biology, computational genomics and explainable AI, drawn from UK university research groups, underpinned by an experienced board and management team with successful exits.